Achievements

REVIEW ARTICLES

2025

Non-Invasive Detection of Tumors by Volatile Organic Compounds in Urine

Tomoaki Hara, Sikun Meng, Yasuko Arao, Yoshiko Saito, Kana Inoue, Aya Hasan Alshammari, Hideyuki Hatakeyama, Eric di Luccio, Andrea Vecchione, Takaaki Hirotsu, and Hideshi Ishii

Biomedicines 2025, 13(1), 109; https://doi.org/10.3390/biomedicines13010109

2024

Overcoming Challenges in Cancer Care: A Focus on Emerging Technologies

Aya Hasan Alshammari, Takaaki Hirotsu, Eric di Luccio

Biomedicines 2024, 12(12), 2787; https://doi.org/10.3390/biomedicines12122787

N-NOSE Proves Effective for Early Cancer Detection: Real-World Data from Third-Party Medical Institutions

Nobushige Nakajo, Hideyuki Hatakeyama, Masayo Morishita, and Eric di Luccio

Biomedicines 2024, 12(11), 2546; https://doi.org/10.3390/biomedicines12112546

Bridging the gap in cervical cancer screening for underserved communities: MCED and the promise of future technologies

Aya Hasan Alshammari, Hideshi Ishii, Takaaki Hirotsu, Hideyuki Hatakeyama, Masayo Morishita, Eric di Luccio

Frontiers in Oncology 2024 Jul 29:14:1407008 doi: 10.3389/fonc.2024.1407008.

Publication of Groundbreaking Review on Tissue-Resident Memory T Cells in Gastrointestinal Cancers

Hiromichi Sato, Sikun Meng, Tomoaki Hara, Yoshiko Tsuji, Yasuko Arao, Kazuki Sasaki, Shogo Kobayashi, Eric di Luccio, Takaaki Hirotsu, Taroh Satoh, Yuichiro Doki, Hidetoshi Eguchi, and Hideshi Ishii

Biomedicines 2024, 12, 1342 https://www.mdpi.com/2227-9059/12/6/1342

2023

State-of-the-Art Cancer Biology, Biodiagnostics and Therapeutics in Japan

Junichi Yamaguchi, Eric di Luccio*, and Takaaki Hirotsu

Invited editorial to the Specia Issue, Biomedicines 2023, 11(11), 2905; https://doi.org/10.3390/biomedicines11112905

Pancreatic Cancer and Detection Methods

Umbhorn Ungkulpasvich, Hideyuki Hatakeyama, Takaaki Hirotsu, Eric di Luccio

Biomedicines 2023, 11(9), 2557; https://doi.org/10.3390/biomedicines11092557

2022

Pancreatic Cancer Research beyond DNA Mutations

Hiromichi Sato, Kazuki Sasaki, Tomoaki Hara, Yoshiko Tsuji, Yasuko Arao, Chihiro Otsuka, Yumiko Hamano, Mirei Ogita, Shogo Kobayashi, Eric di Luccio, Takaaki Hirotsu, Yuichiro Doki, Hidetoshi Eguchi, Taroh Satoh, Shizuka Uchida and Hideshi Ishii

Biomolecules 2022, 12, 1503. https://doi.org/10.3390/biom12101503

C. elegans as a Powerful Tool for Cancer Screening

Eric di Luccio, Masayo Morishita and Takaaki Hirotsu

Biomedicines 2022, 10(10), 2371; https://doi.org/10.3390/biomedicines10102371

Nematode-Applied Technology for Human Tumor Microenvironment Research and Development

Eric di Luccio, Satoru Kaifuchi, Nobuaki Kondo, Ryota Chijimatsu, Andrea Vecchion, Takaaki Hirotsu* and Hideshi Ishii*

Curr. Issues Mol. Biol. 2022, 44(2), 988-998; https://doi.org/10.3390/cimb44020065

2021

Impact of One-Carbon Metabolism-Driving Epitranscriptome as a Therapeutic Target for Gastrointestinal Cancer

Yu Takeda, Ryota Chijimatsu, Andrea Vecchione, Takahiro Arai, Toru Kitagawa, Ken Ofusa, Masami Yabumoto, Takaaki Hirotsu, Hidetoshi Eguchi, Yuichiro Doki and Hideshi Ishii*

International Journal of Molecular Sciences 2021, 22(14), 7278 https://doi.org/10.3390/ijms22147278

2020

Immuno-Surgical Management of Pancreatic Cancer with Analysis of Cancer Exosomes

Yu Takeda ,Shogo Kobayashi ,Masatoshi Kitakaze ,Daisaku Yamada ,Hirofumi Akita ,Ayumu Asai ,Masamitsu Konno ,Takahiro Arai ,Toru Kitagawa ,Ken Ofusa ,Masami Yabumoto ,Takaaki Hirotsu ,Andrea Vecchione ,Masateru Taniguchi ,Yuichiro Doki ,Hidetoshi Eguchi and Hideshi Ishii*

Cells 2020, 9(7), 1645; doi:10.3390/cells9071645

State-of-the-Art Technology of Model Organisms for Current Human Medicine

Masamitsu Konno, Ayumu Asai, Toru Kitagawa, Masami Yabumoto, Ken Ofusa, Takahiro Arai, Takaaki Hirotsu, Yuichiro Doki, Hidetoshi Eguchi and Hideshi Ishii*

Diagnostics 2020, 10, 392; doi:10.3390/diagnostics10060392

2019

Learning from nematodes

Dr Takaaki Hirotsu and Dr Hideshi Ishii

Impact

2016

A new method for time and cell-specific RNAi

Hamakawa M., Hirotsu T.

Methods in Molecular Biology, 1507(67-79)